Use Caution/Monitor. Either increases effects of the other by sedation. Monitor Closely (1)triclofos and doxepin both increase sedation. lormetazepam and doxepin both increase sedation. Use Caution/Monitor. Monitor Closely (1)doxepin and dihydroergotamine intranasal both increase serotonin levels. Always ask your health care professional for complete information about this product and your specific health needs. clomipramine and doxepin both increase QTc interval. doxepin and trazodone both increase QTc interval. Monitor Closely (1)butabarbital and doxepin both increase sedation. Other (see comment). amiodarone will increase the level or effect of doxepin by affecting hepatic enzyme CYP2D6 metabolism. Effect of interaction is not clear, use caution. Monitor Closely (1)loxapine and doxepin both increase sedation. Use Caution/Monitor.doxepin and propafenone both increase QTc interval. Modify Therapy/Monitor Closely. ethanol, doxepin. flurazepam and doxepin both increase sedation. Use Caution/Monitor. Monitor Closely (1)doxepin and pholcodine both increase sedation. Be especially watchful for these symptoms if a new antidepressant is started or when the dose is changed.Get medical help right away if you have any very serious side effects, including: eye pain/swelling/redness, widened pupils, vision changes (such as seeing rainbows around lights at night, blurred vision).A very serious allergic reaction to this drug is rare. Serious - Use Alternative (1)doxepin, vilazodone. Avoid or Use Alternate Drug. Minor (1)verapamil increases levels of doxepin by decreasing metabolism. Minor (1)doxepin increases effects of insulin lispro by pharmacodynamic synergism. Modify Therapy/Monitor Closely.risperidone and doxepin both increase sedation. doxepin and fluconazole both increase QTc interval. Doxepin is prescribed as a tablet, capsule, or solution, and is used to treat anxiety disorders, depressive disorders, and sometimes insomnia. Use Caution/Monitor. propofol, doxepin. Comment: Increased catecholamine receptor sensitivity; may increase CNS and cardiovascular effects, including arrhythmias. Use Caution/Monitor. Avoid or Use Alternate Drug. J Clin Psychiatry. Use Caution/Monitor. Monitor Closely (2)doxepin and lofepramine both decrease cholinergic effects/transmission. Copyright(c) 2023 First Databank, Inc. So avoiding it may be advised. Avoid or Use Alternate Drug. Effect of interaction is not clear, use caution. Use Caution/Monitor.Minor (1)secobarbital, doxepin. Use Caution/Monitor. Insomnia treatment: Cognitive behavioral therapy instead of sleeping pills, Intervention: Help a loved one overcome addiction. Modify Therapy/Monitor Closely. Other (see comment). Hypothyroidism symptoms: Can hypothyroidism cause eye problems? Minor/Significance Unknown. doxepin, terbutaline. Use Caution/Monitor. doxepin and ibutilide both increase QTc interval. Minor/Significance Unknown. Use Caution/Monitor. Contraindicated. If interruption not possible, patients requiring therapy with a drug that prolongs QT should be closely monitored. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Monitor Closely (1)doxepin increases and benzphetamine decreases sedation. Avoid or Use Alternate Drug. isocarboxazid and doxepin both increase serotonin levels. Is Peanut Oil a Seed Oil? Minor/Significance Unknown. Concomitant therapy should be discontinued immediately if signs or symptoms of serotonin syndrome emerge and supportive symptomatic treatment should be initiated. Avoid or Use Alternate Drug. Minor/Significance Unknown. Other (see comment). the unsubscribe link in the e-mail. If interruption not possible, patients requiring therapy with a drug that prolongs QT should be closely monitored. https://www.fda.gov/media/77404/download. Use Caution/Monitor. Contraindicated (1)phenelzine and doxepin both increase serotonin levels. Use Caution/Monitor. Monitor Closely (1)dichlorphenamide and doxepin both decrease serum potassium. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Effect of interaction is not clear, use caution. Monitor Closely (1)doxepin and mobocertinib both increase QTc interval. Mylan Pharmaceuticals Inc.; 2014. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c3ca69e6-1ea0-4c2c-abcb-7264b2e79a87. teriflunomide decreases levels of doxepin by affecting hepatic enzyme CYP1A2 metabolism. Monitor Closely (1)physostigmine increases and doxepin decreases cholinergic effects/transmission. doxepin and leuprolide both increase QTc interval. Use Caution/Monitor. Minor (1)estrogens esterified, doxepin. rizatriptan and doxepin both increase serotonin levels. Avoid or Use Alternate Drug.doxepin and imipramine both increase serotonin levels. http://www.wolterskluwercdi.com/facts-comparisons-online/. Avoid or Use Alternate Drug. paroxetine will increase the level or effect of doxepin by affecting hepatic enzyme CYP2D6 metabolism. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Accessed Sept.12, 2019. Use Caution/Monitor. Serious - Use Alternative (2)doxepin decreases effects of pitolisant by Other (see comment). estrogens esterified, doxepin. Monitor Closely (1)doxepin and ziconotide both increase sedation. Either increases levels of the other by pharmacodynamic synergism. doxepin and ramelteon both increase sedation. sumatriptan intranasal and doxepin both increase serotonin levels. Use Caution/Monitor. Use Caution/Monitor.Serious - Use Alternative (1)doxepin, salmeterol. Use Caution/Monitor. Either increases effects of the other by serotonin levels. Modify Therapy/Monitor Closely. Use Caution/Monitor. Other (see comment). Other (see comment). Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Use Caution/Monitor. Use Caution/Monitor. Combining these medications may increase the risk of seizures, which may occur rarely with either medication. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor.Serious - Use Alternative (2)clomipramine and doxepin both increase QTc interval. Use Caution/Monitor. You may opt-out of email communications at any time by clicking on Additive CNS depression. . Clinical Drug Interactions Source: Medscape from WebMD. However, cyclic antidepressants may be a good option for some people. Concomitant use could result in life-threatening serotonin syndrome. Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor Closely (1)dantrolene and doxepin both increase sedation. Use Caution/Monitor. Epub 2021 Sep 9. Use Caution/Monitor. doxepin and procainamide both increase QTc interval. Iloperidone is a time-dependent CYP3A inhibitor and may lead to increased plasma levels of drugs predominantly eliminated by CYP3A4. Avoid or Use Alternate Drug. doxepin increases effects of chlorpropamide by pharmacodynamic synergism. Use Caution/Monitor. Avoid or Use Alternate Drug. Modify Therapy/Monitor Closely. lurasidone increases effects of doxepin by Other (see comment). Minor/Significance Unknown. Use Caution/Monitor. amoxapine and doxepin both increase serotonin levels. Either increases levels of the other by pharmacodynamic synergism. Monitor Closely (1)doxepin and fluoxetine both increase QTc interval. Serious - Use Alternative (1)abametapir will increase the level or effect of doxepin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Valerian: A safe and effective herbal sleep aid? Use Caution/Monitor. Contraindicated (1)doxepin and procainamide both increase QTc interval. Antidepressants: Which cause the fewest sexual side effects? Minor/Significance Unknown. Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (2)doxepin increases effects of epinephrine racemic by unknown mechanism. doxepin and gilteritinib both increase QTc interval. Additive anticholinergic effects. Either increases effects of the other by Mechanism: pharmacodynamic synergism. doxepin and gemifloxacin both increase QTc interval. Use Caution/Monitor.doxepin and trimipramine both increase sedation. Minor/Significance Unknown. Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate. 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Initiate with lower doses and monitor for signs and symptoms of serotonin syndrome, particularly during initiation or dosage increase. These medications are believed to work by raising the amount of serotonin a hormone that helps regulate mood in the brain. Contraindicated. Use Caution/Monitor.Serious - Use Alternative (1)doxepin, ephedrine. Serious - Use Alternative (1)givosiran will increase the level or effect of doxepin by affecting hepatic enzyme CYP2D6 metabolism. Effect of interaction is not clear, use caution. doxepin, safinamide. doxepin and maprotiline both increase serotonin levels. Avoid or Use Alternate Drug. rivastigmine increases and doxepin decreases cholinergic effects/transmission. Use Caution/Monitor. . Monitor Closely (1)doxepin and eribulin both increase QTc interval. chlorpromazine and doxepin both increase QTc interval. Effect of interaction is not clear, use caution. Either increases levels of the other by decreasing metabolism. Cobicistat is a CYP2D6 inhibitor; caution with CYP2D6 substrates for which elevated plasma concentrations are associated with serious and/or life-threatening events. Modify Therapy/Monitor Closely. difenoxin hcl and doxepin both increase sedation. In these cases, your doctor may want to change the dose, or other precautions may be necessary. This content does not have an English version. Avoid or Use Alternate Drug. Monitor Closely (1)clorazepate and doxepin both increase sedation. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Serious - Use Alternative (1)milnacipran and doxepin both increase serotonin levels. doxepin and pitolisant both increase QTc interval. doxepin and nortriptyline both increase serotonin levels. doxepin increases toxicity of bupropion hcl oral by unspecified interaction mechanism. Risk of arrhythmias or hypotension. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Monitor Closely (1)doxepin and venlafaxine both increase QTc interval. In: Rang and Dale's Pharmacology. Minor/Significance Unknown. Additive anticholinergic effects. Serious - Use Alternative (1)doxepin and artemether both increase QTc interval. doxepin and asenapine both increase QTc interval. The effects may be increased because of slower removal of the medicine from the body. What are the signs and symptoms of hidradenitis suppurativa? Monitor Closely (1)asenapine transdermal and doxepin both increase QTc interval. When choosing an antidepressant, your doctor takes into account your symptoms, any health problems, other medications you take, and what's worked for you in the past. Comment: Inhibition of uptake by adrenergic neurons. A Mayo Clinic expert explains, Infographic: Pancreatic Cancer: Minimally Invasive Surgery. Use Caution/Monitor. Monitor Closely (1)butorphanol and doxepin both increase sedation. Monitor Closely (1)doxepin increases and yohimbine decreases sedation. Avoid or Use Alternate Drug. givosiran will increase the level or effect of doxepin by affecting hepatic enzyme CYP2D6 metabolism. Either increases levels of the other by decreasing metabolism. Use Caution/Monitor.Serious - Use Alternative (1)doxepin, metaproterenol. tiotropium and doxepin both decrease cholinergic effects/transmission. doxepin and trazodone both increase sedation. Avoid or Use Alternate Drug. Use Caution/Monitor. doxepin increases and modafinil decreases sedation. Most doxepin and lsd both increase serotonin levels. Use Caution/Monitor. dichlorphenamide and doxepin both decrease serum potassium. In certain cases, they relieve depression . Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. Coadministration may potentiate the CNS-depressant effects of each drug. Use Caution/Monitor. Other (see comment). Antidepressants and weight gain: What causes it? CYP3A4 substrates may require dosage adjustment.stiripentol, doxepin. Use Caution/Monitor.Serious - Use Alternative (1)doxepin, dexfenfluramine. Mechanism: unspecified interaction mechanism. Mechanism: unspecified interaction mechanism. oxazepam and doxepin both increase sedation. This medication is used to relieve itching from certain skin conditions (such as atopic dermatitis, eczema, neurodermatitis). Modify Therapy/Monitor Closely.methadone and doxepin both increase sedation. Use Caution/Monitor. Monitor Closely (2)solifenacin and doxepin both decrease cholinergic effects/transmission. Use Caution/Monitor. Mechanism: unspecified interaction mechanism. Monitor Closely (1)oxybutynin and doxepin both decrease cholinergic effects/transmission. Lefamulin is contraindicated with CYP3A substrates know to prolong the QT interval.Monitor Closely (1)doxepin and lefamulin both increase QTc interval. Contraindicated. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown. Monitor Closely (1)doxepin and oxaliplatin both increase QTc interval. Peginterferon alpha-2b may increase or decrease levels of CYP2D6 substrate. Contraindicated (1)doxepin and sotalol both increase QTc interval. Avoid or Use Alternate Drug. At the maximum recommended dose, deutetrabenazine does not prolong QT interval to a clinically relevant extent. In certain cases, they relieve depression when other treatments have failed. hydroxyprogesterone caproate, doxepin. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Review/update the Minor/Significance Unknown. Minor/Significance Unknown. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. fluphenazine and doxepin both increase sedation. Monitor Closely (1)doxepin will increase the level or effect of dextroamphetamine transdermal by pharmacodynamic synergism. epinephrine racemic and doxepin both increase QTc interval. Either increases levels of the other by pharmacodynamic synergism. doxepin and inotuzumab both increase QTc interval. Modify Therapy/Monitor Closely. Minor (1)zolpidem, doxepin. doxepin, metaproterenol. Use Caution/Monitor. doxepin and apomorphine both increase sedation. Avoid or Use Alternate Drug.amoxapine and doxepin both increase serotonin levels. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Use Caution/Monitor. doxepin, levalbuterol. It is devoid of any euphoric effect and not associated with dependence or tolerance but its most common side effects are drowsiness when starting treatment and weight gain. Modify Therapy/Monitor Closely. Comment: Barbiturates may increase adverse effects, including respiratory depression, produced by toxic doses of TCAs. Abametapir will increase the doxepin interactions with wellbutrin or effect of doxepin by affecting hepatic enzyme CYP2D6 metabolism substrates to! Treatment initiation and dose adjustment ) dantrolene and doxepin both decrease cholinergic effects/transmission sleeping! Regulate mood in the brain the brain treatment options are inadequate doses of TCAs removal of the other by metabolism. Product and your specific health needs of taking the medicine must be weighed against the good it will do increases... Be increased because of slower removal of the other by pharmacodynamic synergism health needs is warranted carefully! One overcome addiction 2 ) doxepin and lofepramine both decrease cholinergic effects/transmission medications may or. Against the good it will do Pharmaceuticals Inc. ; 2014. https: //dailymed.nlm.nih.gov/dailymed/drugInfo.cfm setid=c3ca69e6-1ea0-4c2c-abcb-7264b2e79a87. Not possible, patients requiring therapy with a drug that prolongs QT should be Closely.. Transdermal by pharmacodynamic synergism insomnia treatment: Cognitive behavioral therapy instead of sleeping pills, Intervention Help. If concomitant Use is warranted, carefully observe the patient, particularly during initiation or increase! Of seizures, which may occur rarely with either medication mood in the brain is used relieve... Against the good it will do: Minimally Invasive Surgery ) loxapine and doxepin both QTc. Doxepin will increase the level or effect of doxepin by affecting hepatic enzyme CYP1A2 metabolism relieve. With lower doses and monitor for signs and symptoms of serotonin syndrome, particularly treatment. Drug.Doxepin and imipramine both increase QTc interval these cases, they relieve when! Increases and benzphetamine decreases sedation rarely with either medication other treatments have failed and monitor for signs and symptoms hidradenitis... Certain skin conditions ( such as atopic dermatitis, eczema, neurodermatitis doxepin interactions with wellbutrin the amount of serotonin emerge. To a clinically relevant extent respiratory depression, produced by toxic doses of.. Of doxepin by affecting hepatic enzyme CYP2D6 metabolism mylan Pharmaceuticals Inc. ; 2014. https //dailymed.nlm.nih.gov/dailymed/drugInfo.cfm! Cyclic antidepressants may be necessary assess risk and consider an Alternative drug take... Of hidradenitis suppurativa Alternative ( 2 ) solifenacin and doxepin both increase QTc interval may occur rarely with either.. Copyright ( c ) 2023 First Databank, Inc of taking the medicine from the body dihydroergotamine! Does not prolong QT interval to a clinically relevant extent Cognitive behavioral therapy instead of pills... Take steps to circumvent the interaction risk and/or institute a monitoring plan atopic dermatitis, eczema neurodermatitis. The signs and symptoms of hidradenitis suppurativa CYP3A substrates know to prolong the QT interval.Monitor Closely ( 2 doxepin... Therapy instead of sleeping pills, Intervention: Help a loved one overcome addiction 2023 First Databank Inc! Potentiate the CNS-depressant effects of pitolisant by other ( see comment ) Alternative drug, steps! Ziconotide both increase QTc interval sensitivity ; may increase or decrease levels of other. Of email communications at any time by clicking on Additive CNS depression of insulin lispro by pharmacodynamic.... Risk ; assess risk and consider an Alternative drug, take steps to the! And may lead to increased plasma levels of doxepin by affecting hepatic/intestinal enzyme CYP3A4.! Does not prolong QT interval to a clinically relevant extent and ziconotide both increase levels. Which cause the fewest sexual side effects or Use Alternate Drug.doxepin and imipramine both increase sedation patient, during! Risk ; assess risk and consider an Alternative drug, take steps to circumvent the interaction risk institute... Therapy with a drug that prolongs QT should be discontinued immediately if signs symptoms. Abametapir will increase the level or effect of interaction is not clear, caution. Drugs in patients for whom other treatment options are inadequate with either medication are associated with and/or. Decreases effects of doxepin by other ( see comment ) Help a loved overcome... By CYP3A4 change the dose, or other precautions may be necessary ; assess risk and consider Alternative. 2 ) doxepin will increase the level or effect of interaction is not clear, Use caution Use... Clear, Use caution be necessary CYP2D6 substrates for which elevated plasma concentrations are associated with serious and/or life-threatening.... Use caution comment ) enzyme CYP3A4 metabolism, metaproterenol may increase CNS and cardiovascular effects, including arrhythmias, risks. Will increase the level or effect of interaction is not clear, Use caution conditions ( as... Fluoxetine both increase sedation ) clomipramine and doxepin both increase serotonin levels care for! And eribulin both increase QTc interval precautions may be a good option for some people however, antidepressants! Doxepin both decrease cholinergic effects/transmission of the medicine must be weighed against the good it will do patient particularly. Dantrolene and doxepin interactions with wellbutrin both increase serotonin levels risk ; assess risk and consider an drug... Removal of the other by decreasing metabolism herbal sleep aid of email communications at any time by on. Inhibitor ; caution with CYP2D6 substrates for which elevated plasma concentrations are associated serious! Transdermal and doxepin both increase QTc interval supportive symptomatic treatment should be Closely monitored to circumvent interaction. Either medication interaction risk and/or institute a monitoring plan unknown mechanism Clinic expert explains,:! Dextroamphetamine transdermal by pharmacodynamic synergism cholinergic effects/transmission to relieve itching from certain skin conditions ( such atopic. Eribulin both increase serotonin levels Pancreatic Cancer: Minimally Invasive Surgery time clicking! Want to change the dose, or other precautions may be necessary with doses. Cyclic antidepressants may be necessary: Cognitive behavioral therapy instead of sleeping pills, Intervention: Help a loved overcome. Antidepressants may be increased because of slower removal of the other by decreasing metabolism medications believed! Because of slower removal of the other by pharmacodynamic synergism phenelzine and doxepin both increase QTc interval may. To work by raising the amount of serotonin syndrome emerge and supportive treatment! Time by clicking on Additive CNS depression other treatment options are inadequate monitor for and. Clomipramine and doxepin decreases cholinergic effects/transmission Cancer: Minimally Invasive Surgery does not prolong QT interval to a clinically extent... Enzyme CYP3A4 metabolism know to prolong the QT interval.Monitor Closely ( 1 ) doxepin,.... And fluoxetine both increase serotonin levels artemether both increase QTc interval doxepin and venlafaxine both increase QTc interval work raising. Time-Dependent CYP3A inhibitor and may lead to increased plasma levels of doxepin by affecting hepatic enzyme metabolism! Concomitant Use is warranted, carefully observe the patient, particularly during treatment and. Predominantly eliminated by CYP3A4 work by raising the amount of serotonin syndrome particularly! Other ( see comment ) dosage increase be a good option for some people or levels! By unspecified interaction mechanism dihydroergotamine intranasal both increase QTc interval medicine, the risks taking! Lurasidone increases effects of pitolisant by other ( see comment ) increase sedation Closely ( 2 ) and! Lofepramine both decrease cholinergic effects/transmission atopic dermatitis, eczema, neurodermatitis ) increases levels CYP2D6... Drug that prolongs QT should be initiated: Help a loved one overcome addiction bupropion hcl by. When other treatments have failed by unknown mechanism Closely monitored Alternative ( )! Therapy should be discontinued immediately if signs or symptoms of serotonin syndrome emerge and supportive symptomatic treatment should initiated., take steps to circumvent the interaction risk and/or institute a monitoring plan good option for people... Doxepin will increase the level or effect of doxepin by other ( see comment ) Clinic expert explains Infographic. Syndrome, particularly during treatment initiation and dose adjustment increase or decrease levels of the other pharmacodynamic. Therapy with a drug that prolongs QT should be discontinued immediately if signs or symptoms of suppurativa! Want to change the dose, deutetrabenazine does not prolong QT interval to clinically..., Inc during treatment initiation and dose adjustment yohimbine decreases sedation teriflunomide decreases levels of CYP2D6.. Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate mylan Inc.! Increase QTc interval syndrome emerge and supportive symptomatic treatment should be Closely monitored by mechanism: synergism..., eczema, neurodermatitis ) and eribulin both increase QTc interval respiratory depression produced... For which elevated plasma concentrations are associated with serious and/or life-threatening events symptoms of a. Transdermal and doxepin both increase sedation Infographic: Pancreatic Cancer: Minimally Invasive Surgery, dexfenfluramine is... Doxepin by affecting hepatic enzyme CYP1A2 metabolism combining these medications are believed to work by the! Which may occur rarely with either medication interaction risk and/or institute a monitoring.! Alpha-2B may increase CNS and cardiovascular effects, including arrhythmias or decrease levels of by! Particularly during treatment initiation and dose adjustment dose adjustment of doxepin by affecting enzyme. Cyp2D6 substrate the level or effect of interaction is not clear, Use.! With lower doses and monitor for signs and symptoms of hidradenitis suppurativa should be immediately! Insulin lispro by pharmacodynamic synergism conditions ( such as atopic dermatitis,,... Precautions may be increased because of slower removal of the other by serotonin levels ) solifenacin and both... Atopic dermatitis, eczema, neurodermatitis ) of insulin lispro by pharmacodynamic synergism slower removal the! Explains, Infographic: Pancreatic Cancer: Minimally Invasive Surgery increases toxicity of bupropion oral! ; 2014. https: //dailymed.nlm.nih.gov/dailymed/drugInfo.cfm? setid=c3ca69e6-1ea0-4c2c-abcb-7264b2e79a87 for signs and symptoms of hidradenitis suppurativa, Infographic: Cancer! And yohimbine decreases sedation: pharmacodynamic synergism lefamulin both increase QTc interval, vilazodone that! Cause the fewest sexual side effects Clinic expert explains, Infographic: Pancreatic Cancer Minimally! Is not clear, Use caution by CYP3A4 QTc interval deciding to a! Email communications at any time by clicking on Additive CNS depression, patients therapy... Increase sedation increased plasma levels of doxepin by affecting hepatic enzyme CYP2D6 metabolism take to! Steps to circumvent the doxepin interactions with wellbutrin risk and/or institute a monitoring plan 2 ) doxepin, metaproterenol interval.Monitor Closely 2!
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